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Sunday Science by Go UnPro Sleep and Aging and Cancer 2026_08_16
Welcome to Sunday Science, where we dive into a few recent scientific articles and their translation into our modern lives. Here is your host, Brent W. Laartz, M.D. Alright everyone, welcome to another Sunday Science Go by GoUnPro, the,... study and multiple different studies. So this is going to be really a fly-by-night thing here. We're going to be looking through six different studies regarding sleep. This is my subject that I am really delving into my own life over the
18 min read


Week 18: A Doctor’s 52 Week Journey to an Unprocessed Life
Welcome to the Go Unpro podcast, a doctor's 52-week journey to an unprocessed life. Now, here is your host Dr. Brent W. Lartz, Associate Professor of Infectious Diseases and Internal Medicine, Neuroscientist, and best-selling author. Alright everyone. here we are week 18 a doctor's 52 week journey to an unprocessed life here we are uh week 18 we've passed the one-third way mark and finding a few hiccups here along the way but mostly success and that's the point to it mostly
30 min read


Sunday Science by Go UnPro 2026_08_09 Variety of Exercise and Longevity
Sunday Science: Longevity and Physical Activity Analysis Summary Of Speaker Contributions Dr. Brent Laartz: Led the session by reviewing multiple scientific studies regarding physical activity and longevity. He introduced the "five pillars" of movement—strength, cardiovascular fitness, flexibility, mobility, balance, and muscular endurance—and synthesized data from cohort studies and meta-analyses to advocate for a diverse exercise routine. Key Points And Decisions Th
24 min read


Week 17: A Doctor’s 52 Week Journey to an Unprocessed Life
Go UnPro: Week 17 Progress and The Comfort Crisis Summary Of Each Speaker Dr. Brent Laartz: Provided a progress update on his 52-week journey toward an unprocessed life. He focused on the psychological and physical benefits of embracing discomfort, the importance of tracking goals, and the ongoing effort to eliminate plastics and processed habits from his daily routine. Key Points And Decisions Goal Reassessment: Dr. Laartz emphasized that goals should not be "set and
27 min read


Sunday Science by GoUnPro 2026_08_02 Protein Restricted Diets
Insights on Protein Restriction and Longevity Summary Of Speaker Contributions Dr. Brent Laartz: Served as the primary presenter, synthesizing findings from over 300 scientific articles regarding protein restriction and its impact on aging. He highlighted the role of nutrient-sensing pathways, such as mTOR and GCN2, and argued that while high protein intake is often marketed for muscle growth, it may negatively impact longevity and metabolic health in older adults. He adv
18 min read


Sunday Science Forever Chemicals and Nanoplastics and Inflammation
Sunday Science: Impact of Microplastics and Forever Chemicals on Human Health Speaker Contributions Dr. Brent Laartz: Acted as the primary subject matter expert, synthesizing three recent scientific studies regarding the health impacts of microplastics and perfluoroalkyl compounds (PFAS). He provided detailed analysis on how these contaminants contribute to inflammation, cellular senescence, and tumorigenesis, while sharing his personal journey toward a "deplasticized" li
20 min read


Week 16: A Doctor’s 52 Week Journey to an Unprocessed Life
Navigating the Comfort Crisis: A Journey to an Unprocessed Life Speaker Contributions Dr. Brent Laartz: Served as the primary speaker, detailing his personal journey through "Week 16" of an unprocessed life. He contributed insights on the psychological and physical impacts of modern comfort, the importance of intentional living, and the rejection of instant gratification in favor of long-term health. Key Points and Decisions The Comfort Crisis: The host argued that mo
21 min read


Week 15: A Doctor’s 52 Week Journey to an Unprocessed Life
The 52-Week Journey to an Unprocessed Life: Week 15 Progress Report Speaker Contributions Dr. Brent Laartz: Acted as the primary contributor, detailing his "dollar cost averaging" philosophy for health. He shared his personal progress on his 52-week journey, emphasizing the importance of consistent daily investments in diet, exercise, sleep, motivation, and connection to secure long-term health. Key Points and Decisions Health as a Retirement Account: Dr. Laartz estab
29 min read


Sunday Science Diet Comparison and Aging 2026_07_12
Sunday Science: Biological Aging and Dietary Patterns Speaker Contributions Dr. Brent Laartz: Presented a detailed analysis of a UK Biobank study involving 400,000 participants. He evaluated the correlation between dietary patterns—specifically regular meat-eating, low-meat, pescatarian, and vegetarian diets—and biological aging using KDM-BA and PhenoAge metrics. Key Points and Decisions Study Findings: The research demonstrated that individuals who consume less meat,
8 min read


Week 14: A Doctor’s 52 Week Journey to an Unprocessed Life
Go UnPro Podcast: Week 14 Summary Dr. Brent Laartz: Provided a comprehensive update on his 52-week journey to an unprocessed life. He detailed his strategies for post-holiday recovery, home-based resistance training, dietary habits, and the reduction of environmental toxins in his new home. Key Points And Decisions Post-Holiday Detox: Dr. Laartz emphasized returning to a routine of fiber, water, and calorie restriction following the July 4th holiday, rather than relying
19 min read


Week 13: A Doctor’s 52 Week Journey to an Unprocessed Life
Go Unpro Podcast: Week 13 Progress Report Speaker Contributions Dr. Brent Laartz: Provided a comprehensive update on his 52-week "unprocessed life" journey, detailing his transition to a new home, dietary modifications, and lifestyle habits centered on longevity. Key Points and Decisions Dietary Shifts: Dr. Laartz decided to completely eliminate beef and pork from his diet, focusing instead on poultry, seafood, beans, and fermented foods to support microbiome health.
16 min read


Week 12: A Doctor’s 52 Week Journey to an Unprocessed Life
Week 12: A Doctor’s 52 Week Journey to an Unprocessed Life Spectacular Speaker-Focused Summary: Go Unpro Podcast Week 12 – Proof of Life, Microbiome Mastery & Unprocessed Progress Dr. Brent Laartz A candid weekly update on personal setbacks (illness, house move) while celebrating small victories. He reinforced the centrality of microbiome health, outlined specific Week 12 targets across diet, movement, sleep, creativity, and plastics reduction, and reviewed cumulative
21 min read


Sunday Science 2026 Episode 7 Microbiome Enhancing Endurance and Strength
Spectacular Speaker-Centric Summary: Unlocking Microbiome Power for Endurance and Strength in Sunday Science Summary of Each Speaker Dr. Brent Laartz: Hosted the discussion on the bidirectional microbiome-exercise relationship, covering mechanisms like lactate clearance and short-chain fatty acid production, citing studies on Veillonella, Lactobacillus salivarius, and Lactobacillus plantarum, and outlining practical takeaways for enhancing performance. Key Points and De
13 min read


Week 11: A Doctor’s 52 Week Journey to an Unprocessed Life
Key Points and Decisions May successes included daily greens/berries, strong time-restricted feeding, good ethanol control, and realignment after setbacks; vegan days averaged 2–3 per week with some packaged-food lapses during on-call weeks. Biological age tested 14 years younger and cardiovascular age 5 years younger despite minor blood-work artifacts from fasting and allergies. Core stack limited to calcium, vitamin D, B12, omega-3, acarbose, and the five pillars (
40 min read


Week 10: A Doctor’s 52 Week Journey to an Unprocessed Life
Week 10: A Doctor’s 52 Week Journey to an Unprocessed Life Week 10 Summary: Microbiome Mastery in a Doctor's 52-Week Unprocessed Life Journey Dr. Brent W. Laartz Reflects on Paris trip (high steps, fiber via fruits/salads, minimal supplements). Focuses on microbiome week: Gut bacteria's role in health/longevity; impacts from ultra-processed foods, red meat (e.g., colibactin-producing E. coli linked to colon cancer 10-20 years pre-diagnosis); promotes plant-based/Medit
2 min read


Meditation Monday Minute 11
Meditation Monday Minute History is Your Friend Embrace the Past Failures, Successes Own Them All. They Are Integral To Everything You Are They Made You The Success You Are. Only If You Rise Up Pull Yourself Up.
1 min read


Week 9: A Doctor's 52 Week Journey to an Unprocessed Life
Week 9: A Doctor’s 52 Week Journey to an Unprocessed Life Week 9 Summary: Dr. Brent Laartz's Unprocessed Journey – Paris Travel Edition Summary by Speaker Dr. Brent Laartz Travel Edition (Paris/France): Week 9 update; praises French culture, food (organic markets, berries, strawberries, chocolate), architecture; notes smoking culture among youth. 5 Pillars Challenges/Adaptations: - Diet: Mostly vegan (3-5 days/week), antioxidants (berries, dark chocolate), local produ
2 min read


Sunday Science Testosterone 2026_04_19
Sunday Science Testosterone 2026_04_19 Sunday Science: Testosterone Therapy – Risks, Benefits & Longevity Debate Summary by Speaker Dr. Brent Laartz Discusses testosterone decline with age (0.4-2.6%/year, 30-50% by 50-60), low T (<250-300 ng/dL) linked to metabolic syndrome, obesity, increased mortality. Reviews studies:- Low T associated with 1.5-2.3x higher all-cause, CV, cancer mortality (2010 European Heart Journal cohort; 2011 JCEM meta-analysis).- Frailty medi
1 min read


Week 8: A Doctor's 52 Week Journey to an Unprocessed Life
Summary of Key Points, Decisions, and Next Steps from Speaker Dr. Brent Laartz Key Points and Decisions: Experienced a setback during a busy period, leading to less exercise and disrupted sleep schedule Embracing setbacks as opportunities for renewal and comeback Aiming for 6 days per week of following the 5 pillars of an unprocessed life Focusing on avoiding processed oils, increasing intake of colorful fruits/vegetables, and finding friends to exercise with Im
30 min read


Meditation Monday Minute 9
Deeply Through The Nose, Breathe In Your Dreams Feel How The Wind Blows, Into Your Lungs, a Gale It Seems All Senses Heightened Acutely, Wind Tickling Your Bronze Skin Palm Leaves Whispering Loudly, Lights Dancing Wildly Like Sin Feel Where Thought and Senses Lie One Center OF Being Now Aware
1 min read


GoUnPro Sunday Science 2026_02_08
Summary of Key Points, Decisions, and Next Steps by Speaker Dr. Brent Laartz Key Points and Decisions: Discussed several recent studies on the association between playing professional sports, particularly American football, and longevity. Highlighted the Copenhagen City Heart Study, which showed that different sports, such as tennis and badminton, can add years to one's life. Reviewed studies on elite athletes, noting that endurance sports and team sports tend to ha
24 min read


Friday Frhymeday: Off The Tracks
Off the Tracks by Brent W. Laartz, MD Off the tracks, peering through window I fear Could hallowed train derail again? Tracks laid a future planned so well, oh dear. I hear screeching metal damage began Fallen deep this time in forsaken hole Can't see daylight from this depth, I dread Dark as night all around me, mercy to my soul Climbing height to emerge may well be dead Deep beneath the surface, can't breathe Large waves above engulf my goal Inundated, lungs depleted, leag
1 min read


Week 7: A Doctor’s 52 Week Journey to an Unprocessed Life
Speaker-Organized Summary Dr. Brent Laartz Key Points and Decisions Reported on last week's package-free challenge, which was not fully successful but led to a full package-free day Acknowledged setbacks around social gatherings and the difficulty of maintaining a package-free week Emphasized the importance of making whole, healthy foods at home to avoid processed items Discussed the debate around protein intake and longevity, noting that animal studies suggest lo
44 min read


Go Un-Pro Sunday Science 2026_02_01
Sunday Science 2026_02_01 Summary of Key Points, Decisions, and Next Steps by Speaker Dr. Brent Laartz Key Points and Decisions: Entrainment involves the use of auditory or visual stimulation to influence brain wave patterns associated with different states of wakefulness, concentration, relaxation, and sleep. Gamma waves (40 Hz) are associated with concentration and wakefulness, while theta and delta waves are associated with relaxation and sleep. Multiple studie
7 min read


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